Manchester United boss Louis van Gaal has revealed that striker Wayne Rooney will miss upcoming fixtures against West Ham United and Wolfsburg.
The Englishman suffered an ankle injury that kept him out of last week's 1-1 draw away at Leicester City.
And he will miss the next two games for the club as he is forced to wait to play his 500th game for the club.
"It was already in the media – Rojo has been injured," van Gaal told MUTV.
"It's his shoulder, the same as last year, in a training session. It's very unfortunate, also in the position of Luke Shaw, so I have a great problem.
"Also the injury of Wayne Rooney is more heavy [serious] than we thought, so neither can play. That's it I think. Jesse Lingard is coming back which is good news. Phil Jones is still injured so we have six injuries.
"It's a nasty injury [for Rooney]. It's been getting worse but we have to let him train to make the ankle stronger, that's very important.
"I cannot say [how long he's out for] because the doctor shall decide that with Wayne of course. He is training well in the rehabilitation.
"He shall not play his 500th [Manchester United] game. The problem is when you see our injuries they are always contact injuries and you cannot afford that."