Manchester United boss Louis van Gaal has confirmed that goalkeeper David De Gea and winger Antonio Valencia will not feature against San Jose Earthquakes on Tuesday.
The two did not play against Club America last week and will also miss the second International Champions Cup match for the Red Devils.
The Spanish goalkeeper is expected to be fit to face Barcelona on Saturday.
"They are minor injuries so they have visited the hospital this morning," the Dutchman revealed.
"It is confirmed they cannot play against San Jose, I think, but I think we have to wait.
"[Against San Jose Earthquakes it will be] the same line-up in the first half and the second half, only Sam Johnstone shall play 90 minutes because we don't take any risks with the other two goalkeepers."