Manchester City boss Manuel Pellegrini has confirmed that attacking midfielder Samir Nasri will be in the squad to face Southampton today.
The Frenchman will be joined by England's Raheem Sterling as the Citizens continue their quest to finish in the Top Four.
Midfielder Yaya Toure is expected to start on the bench against Real Madrid on Wednesday with Spain's David Silva ruled out for three weeks.
"David [Silva] has a small hamstring injury so he will not be fit for this week," Pellegrini said.
"He needs two or three weeks to recover. Yaya [Toure] starts working today - we'll see the way he improves through the weekend - we'll see if he's fit on Wednesday. He has some option.
"All of the other players are fit.
"Samir [Nasri] worked this week without a problem - he will be in the squad list for Sunday.
"We need the whole squad to play both competitions - Raheem [Sterling] is just coming back from an important muscle injury which is why he's playing just some minutes. If we have the best of him for the next four or five games, we'll be happy.
"We have two different competitions - one is the Premier League where we want to be as near to the top of the table as we can and the other is to try and reach that final.
"The best way to play on Wednesday is to play well and win on Sunday.
"I said before we knew we were going to play eight games in 30 days which is a lot for this squad so I'm making rotations in every game we play.
"I don't understand why having so many games in this league with so much interest why we cannot play 24 hours earlier - at least the same as Real Madrid. It's not for me to say and there's a lot of things like the rights of TV, so I don't know.
"As a manager you always want to have all of the options - we're representing England and the Premier League in the Champions League - at least you don't want to give an advantage to the other team."