Manchester City boss Manuel Pellegrini says seven players will miss tomorrow's key game at home against Tottenham Hotspur.
The Citizens desperately need all three points to keep in touch with the top of the table and will be boosted by the return of defender Vincent Kompany.
Fullback Bacary Sagna and midfielder Fabian Delph are however ruled out.
"It's a long injury list - Sagna, Mangala, Delph, Nasri, Navas, De Bruyne and Bony are out. David Silva is OK," Pellegrini explained.
"We'll see what the starting XI is tomorrow - we're not just thinking about one player and one game, we're involved in a lot of competitions. Maybe we have a lot of criticism when we don't play well but I'm happy with the squad over the whole season.
"You've seen Kompany play for so many years I don't have to say what qualities he brings, he's one of the best defenders in the league.
"Every player must play a game when they're 100%. Vincent has worked for three weeks with no problems. He played 45 minutes in a friendly game against the under-21s and I think he's ready to play.
"Bacary had last week a problem in his knee - some liquid in his knee. He needs an injection and one week at least to return to work.
"Delph is worse as he has a problem with his achilles tendon. He needs six or seven weeks to recover.
"It's difficult with so many injuries in the same position. Unfortunately, that's part of the season and we must try to manage with the players we have."