Chelsea interim manager says defender John Terry could be back for next week's Premier League game away at Southampton.
The 35-year-old did not feature in mid-week against Paris Saint-Germain and is ruled out of tomorrow's FA Cup game against Manchester City.
Young Matt Miazga could make his debut for the club against the Citizens.
"He [John Terry] will not be fit for this weekend," Hiddink revealed.
"I saw him this morning, he worked with the physios and yesterday he tried to do a bit on the pitch but he has too many issues to be fit for the weekend.
"I hope next weekend he will be available. I cannot predict it, we have to be cautious with him as he likes to be there every day but we must be careful.
"Of course it's a disappointment because he's the leader of the team. On the other hand I'm not going to complain or moan because the guys who are taking his place have my full confidence. In Paris they produced a decent performance.
"[Matt] Miazga is close, we are doing some tests but he should be fit. What will the weekend bring? It's too early to say.
"He [Eden Hazard] was in a difficult situation but he has to step up, he knows that,' said the Dutchman. 'I don't like broad talks but sometime small conversations.
"I hope he will step up as soon as possible. I remember he had a sprint on our right-hand side (on Tuesday), that's the old Hazard and what we want to see. He can show more and he's aware of that, it's up to him to step up.
"He's very keen to be here, he's extended his contract, he's happy here and his family is happy here. We will encourage him and talk to him about his performances as we do with all the team."