Arsenal manager Arsene Wenger says attacking midfielder Alexis Sanchez could start on the bench against Watford on Saturday.
The 26-year-old featured for his national team during the international break and will be assessed on Saturday morning by the Arsenal medical team.
The Frenchman also confirmed that midfielder Jack Wilshere and striker Danny Welbeck will not be back before the start of the new year.
"The only thing today is Koscielny has a definite test to see if he is available or not [for the Watford game]," Wenger told the club's official website.
"At the time [Mikel] Arteta and [Mathieu] Flamini will certainly be available for selection. We have three players who could come back and be available again and I don't think we lost anybody from our last game.
"They [Jack Wilshere and Danny Welbeck] are progressing well. Danny Welbeck at the earliest will be back [at the] beginning of January.
"I cannot do a lot about it [Alexis Sanchez playing for Chile].
"He came off as you have seen against Manchester United with a hip problem, a problem with the rotator muscle and he wanted to go.
"He played in the last two games and we have to see how he comes back but it is always a tricky situation Chile are trying to qualify for the World Cup and he is an important player for them but they will use him if they can.
"He is a guy that always wants to play so I knew that was always going to be a tricky situation.
"We have to see if we have to protect him in our next game or not."