Arsenal boss Arsene Wenger says midfielders Alex Oxlade-Chamberlain and Mikel Arteta will be back next month.
The Spaniard last played on 26 November in a 2-0 win over Borussia Dortmund.
The Englishman suffered a grade one hamstring tear in a 2-1 win over Manchester United last week in the FA Cup.
They are both expected to be back for the April 11 away game at Burnley in the Premier League.
"It's a classic hamstring [problem for Alex Oxlade-Chamberlain]," Wenger said.
"That means he will be out for three weeks, four weeks maximum. He will not be available for England as well.
"It's very frustrating for him because he played more games than ever this season. In the last two months I feel he was a bit in and out.
"He has shown again on Monday night what an important player he can be for Arsenal and for England. It's a shame that in the final sprint and he's not there.
"It is affecting him because he loves to play. He is keen to play for England and I think it is a big blow for him. He knows as well that it is the type of injury where you can recover quickly and come back. But it is not an ideal moment.
"I don't know how long it will be before he [Jack Wilshere] returns because we have to respect the progression of his training.
"[Mathieu] Flamini is back in the group today and available for selection. Gabriel should be back on Sunday.
"In fact he's [Mikel Arteta] in full training today. I think three weeks."
